This page benchmarks the performance of a collection of matrix libraries most of which are intended for use with WebGL:
glMatrix (v3.4.0, 2023-4-11), mjs (rev 16, 2010-12-15), CanvasMatrix, EWGL_math (rev 32, 2011-03-15), the math utilities in Google's Closure (svn rev: 1364, 2011-11-3), tdl (commit: 59d484f, 2011-06-03), twgl.js (v3.3.0, 2017-05-05), wgpu-matrix (v1.0.0, 2023-04-1), and Sylvester (v0.1.3, 2007-07-05).
Benchmarks for each library are run in an iframe. Results measure millions of iterations per second of the target operation.

LibraryMultiplicationTranslationScalingRotation (Arbitrary axis)Rotation (X axis)TransposeInverseVector TransformationAverage
glMatrix-float6421.1638.5146.4635.37
glMatrix21.1838.4946.3635.34
glMatrix-native20.8338.5446.4835.28

Adapted by Stephen Bannasch from the benchmarks Brandon Jones created in his glmatrix library.
Additional improvements by Gregg Tavares.
Sylvester benchmarks by Felix E. Klee.
JavaScript Plotting library: Flotr; Sortable Table by Andrew Tetlaw.
The source code for these benchmarks can be found here on github. Pull requests quite welcome!



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Multiplication
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glMatrix-native - Avg: 20826666 iterations per second, Min: 18170000 iterations per second, Max: 21310000 iterations per second

glMatrix-float64 - Avg: 21157000 iterations per second, Min: 19490000 iterations per second, Max: 21386666 iterations per second

glMatrix - Avg: 21176000 iterations per second, Min: 19580000 iterations per second, Max: 21433333 iterations per second

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Translation
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glMatrix-native - Avg: 38543666 iterations per second, Min: 37026666 iterations per second, Max: 38840000 iterations per second

glMatrix-float64 - Avg: 38506666 iterations per second, Min: 36683333 iterations per second, Max: 38893333 iterations per second

glMatrix - Avg: 38493000 iterations per second, Min: 36376666 iterations per second, Max: 38856666 iterations per second

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Scaling
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glMatrix-native - Avg: 46482000 iterations per second, Min: 43513333 iterations per second, Max: 46900000 iterations per second

glMatrix-float64 - Avg: 46461333 iterations per second, Min: 43696666 iterations per second, Max: 46913333 iterations per second

glMatrix - Avg: 46355666 iterations per second, Min: 42990000 iterations per second, Max: 46843333 iterations per second